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Applications: glycosyltransferasesglycosidasesxeno- and allotransplantationhisto- and cytochemistryvirology and microbiologyMAbsglyco-particlesglyco-surfacesaffinity electrophoresisaffinity adsorbentsspecialized list of the ligandspharmaceutically relevant products
Applications > pharmaceutically relevant products
ligand nr.Designation, systematic or trivial name of the ligandbiological rolepotential application
Monosaccharide ligands
0026α-D-mannose-6-phosphateTransport of lysosomal enzymes.
Receptor for pathogenic microorganisms		1) anti-dot for cardiotoxins;
2) targeting
0029β-N-acetyl-D-glucosamineCarbohydrate "chain" of nuclei proteins.
Histon-binding properties		targeting to cell nucleus
0030α-N-acetyl-D-galactosamine (Tn)Cancer-associated antigencancer vaccine
cancer diagnostics
0033muramyldipeptide (MDP)

Fragment of bacterial peptidoglycan, immunomodulator

built-in adjuvant for vaccines

0034β-D-galactose-3-sulfateTerminal fragment of various mucin chainstargeting
0035α-N-acetylneuraminic acidTerminal fragment of various glycoprotein and ganglioside carbohydrate chains.
Receptor for patogenic microorganisms		anti-virals
Disaccharide ligands
0001Lac-di-NAc

Typical antigenic determinant of parasites.
Participation in fertilization in mammals
Plays a role in neural signal transduction

1) galectin blocker
2) targeting
3) anti-parasite
0047LacNAcPutative shared determinant for galectins1) galectin blocker
2) targeting
0048TFCancer-associated antigencancer vaccine
0051Fs-2Xeno- and cancer-associated antigenxenotransplantation
0052core 5Cancer-associated antigencancer vaccine
0053TααCancer-associated antigencancer vaccine
0056TββCancer-associated antigencancer vaccine
0057(GlcNAc)2

Receptor for patogenic microorganisms

1) targeting
2) cancer vaccine

0058SiaTnCancer-associated antigencancer vaccine, cancer diagnostics
00673'-su-LacNAcTerminal fragment of various mucin chains1) anti-metastasis
2) cancer targeting
0072(Sia)2Receptor for siglecs. Plays a role in neural signal transduction1) siglec blocker
2) neuropaties
0088BdiMain xenoantigen1)xenotransplantation
2) vaccines
0091HdiLigand for galectins1) targeting
2) anti-metastasis
3) regulation of fertilization
0097core 3Cancer-associated antigenanti-cancer
0098core 6Cancer-associated antigenanti-cancer
Trisaccharide ligands
00636'-SL

Siglec receptor
Receptor for patogenic microorganisms

1) anti-virals (influenza)
2) anti-dot (Bordella pertussis)

0010Galα1-3'LacXenoantigen1)xenotransplantation
2) vaccines
0005GA1, GgOse3Cancer-associated antigen
Receptor for patogenic microorganisms		1) cancer vaccine, cancer diagnostics
2) anti-bacterial (P. aeruginosa, Strptococcus pneumoniae)
0008P1

Blood group antigen
Receptor for patogenic microorganisms

1) blood typing, transplantation
2) anti-bacterial (Streptococcus suis - meningitis)
3) anti-dot (Clostridium difficile, Shigella disenteriae)

0032Man3Receptor for patogenic microorganisms

1)targeting to APC
2)IgA nephropathy

00363'SLNReceptor for patogenic microorganisms1) anti-virals
2) anti-bacterial (Streptococcus suis - meningitis)
0037Pk, Gb3, GbOse3

Blood group antigen
Receptor for patogenic microorganisms

1) blood typing, transplantation
2) toxin blocker
3) anti-bacterial (coli, Strptococcus etc)
4) anti-dot (Clostridium difficile, Shigella dysenteriae)

0040LeaBlood group antigen1) blood typing, transplantation
2) regulation of fertilization
0042Led (H type 1)Blood group antigen1) blood typing, transplantation
2) regulation of fertilization
0044LexCD15targeting
00543'-SiaLecCancer-associated antigen1) cancer vaccine
2) anti-virals
0059H (type 3)

Blood group antigen
Cancer-associated antigen

cancer vaccine antigen
00603'-SL

Siglec receptor
Receptor for patogenic microorganisms

1) anti-virals (influenza, rotavirus, vesicular stomatitis)
2) anti-bacterial (H. pylori, Streptococcus pneumoniae)
00653'-O-su-LeaUnknown1) targeting
2) selectn blocker
3) targeting to APC
00663'-O-su-LexUnknown1) targeting
2) selectin blocker
3) anti-metastasis
4) targeting to APC
0070Galα1-3'LacNAcXenoantigen1) xenotransplantation
2) vaccines
3) anti-dot
(Clostridium difficile)
0073(Sia)3

Siglec receptor
Neurons adhesion

1) cancer vaccine
2) siglec blocker
0075GlcNAcβ1-3'TFCancer-associated antigencancer vaccine
0078core 2Cancer-associated antigencancer vaccine
0085Atri

Blood group antigen

1) blood typing, transplantation, transfusion
2) anti-bacterial (Staphylococcus saprophyticus - urin. tract infections)
0086Btri

Blood group antigen

blood typing,
transplantation,
transfusion
0089H (type 2)Blood group antigen1) blood typing
2) targeting
00963'-sialyl-TF

Siglec receptor
Cancer-associated antigen

1) cancer vaccine
2) polyomavirus, Sendai virus
0099core 4Cancer-associated antigenanti-cancer
09976'SLN

Siglec receptor
Receptor for pathogenic microorganisms

anti-virals
Tetrasaccharide ligands
0004TkCancer-associated antigencancer vaccine, cancer diagnostics
0006A (type 2)

Blood group antigen

1) blood typing, transplantation, transfusion
2) galectin blocker

0007B (type 2)

Blood group antigen

1) blood typing, transplantation, transfusion
2) galectin blocker

00206(GlcNAc)-su-SiaLexSelectin receptorselectin blocker(anti-inflammation)
0017*6(Gal)-su-SiaLexSelectin receptorselectin blocker(anti-inflammation)
0041Leb

Blood group antigen
Receptor for patogenic microorganisms

1) blood typing, transplantation, transfusion
2) regulation of fertilization
3) anti-bacterial (H. pylori)
0045LeyCancer-associated antigencancer vaccine
0061SiaLea

Cancer-associated antigen
Selectin receptor

1) cancer vaccine, cancer diagnostics
2) targeting
3) selectin blocker
0062SiaLex

Cancer-associated antigen
Selectin receptor

1) targeting
2) selectin blocker
0081LNTGalectin receptorgalectin blocker
0082LNnT

Galectin receptor
Blood group antigen

galectin blocker
0970GA1, asialo-GM1

Cancer-associated antigen
Phagocytosis factor

cancer vaccine

Pentasaccharide ligands
0974HNK-1

Plays a role in neural signal transduction

1) neuropaties
2) targeting

09905-OSMPB receptor1)targeting to APC
2)IgA nephropathy
3)anti-HIV
Heptasaccharide ligands
09897-OSMBP receptortargeting
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