FP - Fluorescein-Labelled Polymeric Probes

Probes are designed to reveal lectins (including selectins) directly on cell membranes, organelles, and in cytoplasm. The low fluorescein content does not affect the probe solubility in water but it still allows a reliable probe detection. PAA used as a high molecular weight carrier demonstrated absence of non-specific interaction with cells and it is stable to chemical and proteolytic action. The affinity of the probes is 102-105 higher than that of the corresponding free sugars. PAA is poly[N-(2-hydroxyethyl)acrylamide], this flexible polymer chain behaves as an additional spacer. Mr approx. 30kDa. Carbohydrate content is 20 mol.% Composition of the conjugates is confirmed by acid hydrolysis followed by HPLC of AMC-monosaccharides.

Cat No Description. Short Name Pack (mg) Price in USD Monosaccharide ligands 0000-FP aminoglucitol 0.40 20 0012-FP glucuronic acid 0.40 160 0014-FP β-D-mannose 0.40 96 0016a-FP β-N-acetylneuraminic acid 0.40 161 0021-FP α-D-glucose 0.40 90 0022-FP β-D-glucose 0.40 90 0023-FP α-D-galactose 0.40 90 0024-FP β-D-galactose 0.40 90 0025-FP α-D-mannose 0.40 90 0026-FP α-D-mannose-6-phosphate 0.40 110 0027-FP α-L-fucose 0.40 90 0028-FP α-L-rhamnose 0.40 90 0029-FP β-N-acetyl-D-glucosamine 0.40 90 0030-FP α-N-acetyl-D-galactosamine (Tn) 0.40 90 0031-FP β-N-acetyl-D-galactosamine 0.40 90 0034-FP β-D-galactose-3-sulfate 0.40 110 0035-FP α-N-acetylneuraminic acid 0.40 170 0035a-FP α-N-acetylneuraminic acid 0.40 170 0064-FP β-N-acetyl-D-glucosamine-6-sulfate 0.40 140 0998-FP α-N-acetyl-D-galactosamine-6-sulfate 0.40 140 Disaccharide ligands 0001-FP Lac-di-NAc 0.40 210 0015-FP Galα4GlcNAc 0.40 140 0019-FP maltose 0.40 90 0038-FP Tαβ 0.40 110 0039-FP Galβ3Gal 0.40 110 0043-FP Lec 0.40 110 0046-FP Lac 0.40 90 0047-FP LacNAc 0.40 140 0048-FP TF 0.40 110 0048a-FP TF 0.40 110 0049-FP Fucα3GlcNAc 0.40 110 0050-FP Fucα4GlcNAc, Le 0.40 110 0051-FP Fs-2 0.40 110 0052-FP core 5 0.40 110 0053-FP Tαα 0.40 110 0053a-FP Galα1-3GalNAcα 0.40 110 0055-FP Galα2Gal 0.40 110 0056-FP Tββ 0.40 110 0057-FP (GlcNAc)2 0.40 110 0057a-FP (GlcNAc)2 0.40 110 0057b-FP (GlcNAc)2 0.40 203 0058-FP SiaTn 0.20 350 0067-FP 3'-su-LacNAc 0.40 210 0068-FP 3'-su-Lec 0.40 210 0069-FP melibiose 0.40 110 0072-FP (Sia)2 0.40 210 0076-FP Gal2βGal 0.40 140 0077-FP 6-O-su-LacNAc 0.40 210 0083-FP GM4 0.40 270 0084-FP Neu5Ac6Gal 0.20 350 0087-FP Adi 0.40 140 0088-FP Bdi 0.40 140 0090-FP 6'-O-su-LacNAc 0.40 210 0091-FP Hdi 0.40 140 0092-FP 3'-O-su-TF 0.40 210 0093-FP 6-O-Su-LacdiNAc 0.40 210 0095-FP di-GalNAcβ 0.40 140 0097-FP core 3 0.40 110 0098-FP core 6 0.40 110 0902-FP gentiobiose 0.40 110 0908-FP 6’-Sia-6-Su-LacNAc 0.20 450 0909-FP 4’-Su-LacNAc 0.40 210 0918-FP 4',6'-di-O-su-LacNAc 0.40 210 0983-FP α-Neu5Gc-Tn 0.20 550 0993-FP 3-SiaTn 0.20 350 0999-FP GalNAcfα4GlcNAc 0.40 210 Trisaccharide ligands 0008-FP P1 0.40 270 0010-FP Galα1-3'Lac 0.40 210 0011-FP GlcNAcβ1-2' TF 0.40 210 0032-FP Man3 0.40 210 0036-FP 3'SLN 0.20 450 0037-FP Pk, Gb3, GbOse3 0.40 225 0040-FP Lea 0.40 210 0042-FP Led (H type 1) 0.40 210 0044-FP Lex 0.40 210 0054-FP 3'-SiaLec 0.20 450 0059-FP H (type 3) 0.40 270 0060-FP 3'-SL 0.20 120 0063-FP 6'-SL 0.20 450 0065-FP 3'-O-su-Lea 0.20 450 0066-FP 3'-O-su-Lex 0.20 450 0070-FP Galα1-3'LacNAc 0.40 270 0071-FP GlcNAcα1-3'TF 0.40 270 0073-FP (Sia)3 0.40 210 0075-FP GlcNAcβ1-3'TF 0.40 270 0078-FP core 2 0.40 270 0085-FP Atri 0.40 200 0085a-FP Atri-long 0.40 200 0086-FP Btri 0.40 160 0086a-FP Btri-long 0.40 160 0089-FP H (type 2) 0.40 270 0096-FP 3'-sialyl-TF 0.20 450 0099-FP core 4 0.40 210 0810-FP GlcNAcβ1-3(Fucα1-2)Galβ 0.40 210 0951-FP 6-Su-3’SLN 0.20 350 0958-FP GlcNAcβ1-3`LacNAc 0.40 270 0959-FP isomaltotriose 0.40 110 0982-FP chitotriose 0.40 210 0984-FP 6-SiaTF 0.20 350 0995-FP 3-LacNAc-Tn 0.00 270 0996-FP 6-LacNAc-Tn 0.20 270 0997-FP 6'SLN 0.20 450 Tetrasaccharide ligands 0004-FP Tk 0.40 210 0041-FP Leb 0.40 270 0045-FP Ley 0.40 300 0061-FP SiaLea 0.20 450 0062-FP SiaLex 0.20 450 0081-FP LNT 0.20 270 0082-FP LNnT 0.20 270 0980-FP 6-LacNAc-TF 0.20 450 Pentasaccharide ligands 0074-FP (Sia)5,6 0.40 210 0914-FP SiaLex  (penta) 0.20 490 0994-FP 3,6-(LacNAc)2Tn 0.40 490 Hexasaccharide ligands 0969-FP Leb (hexa) 0.40 300

Please NOTE! that these ligands normally are not available as free amino alkyl glycosides!

Select only saccharides composed from:

matrix   PA or   BP or   BM or   FP saccharides All mono- or   di- or   tri- or   tetra- or   penta- or   other- saccharides containing Any Glc and   Gal and   Gala and   Man and   Fuc and   Rha and   GlcNAc and   GalNAc and   GalNAca and   Neu5Ac and   Neu5Gc and   GlcA and   Mur sorting increasing catalogue number    number of monosaccharide units in description field show Short Name or   Full Name or   Structure